Eleusis evaluates potential of LSD in treating Alzheimer’s Disease
Category: #health  By Mateen Dalal  Date: 2019-12-20
  • share
  • Twitter
  • Facebook
  • LinkedIn

Eleusis evaluates potential of LSD in treating Alzheimer’s Disease

A clinal stage life science company, Eleusis recently announced results from the Phase 1 clinical trial of LSD (Lysergic Acid Diethylamide), demonstrating the potential of the orally administered low doses of the drug for the treatment of Alzheimer’s disease.

The study demonstrates positive data on the pharmacokinetics, pharmacodynamics, tolerability and safety in healthy-older volunteers over a period of 3 weeks. In the past, LSD has shown clinically relevant therapeutic effects in patients afflicted by substance abuse, depression and anxiety. Prior research also suggests that a low dose LSD may have considerable potential in treating Alzheimer’s disease. This trial conducted by Eleusis was the first registered modern clinical trial on low doses of LSD.

Neiloufar Family, Director of Research at Eleusis and the lead investigator in the study was reportedly quoted saying that they are encouraged by the study results as it provides reassuring safety data and that the frequency of adverse events associated with Lysergic Acid Diethylamide is similar to placebo.

Charles Nichols, Professor of Pharmacology at Louisiana State University and co-author of the study was reported to state that this research with serotonin receptor agonists like LSD, represent a new strategy to treat diseases associated with chronic inflammation.

The unique polypharmacology of LSD may serve to enhance its capacity to regulate several key pathological processes in the brain that are associated with Alzheimer’s disease, along with the neuroinflammation, that are implicated in its progression from mild cognitive impairment.

Shlomi Raz, Chairman & Founder, Eleusis. Stated that the company is exhilarated to share the results of the groundbreaking trial of LSD and consider that this study will serve as the foundation for the promising therapeutic development of Lysergic Acid Diethylamide drug and other psychedelic drugs as therapeutics. Raz added that they are looking forward to unravelling the therapeutic potential of psychedelics at non-psychoactive, subperceptual, doses, to safely address the most urgent unmet needs in public health.

Source Credit: https://www.eleusisltd.com/news/2019/12/18/eleusis-announces-phase-1-trial-results-of-lysergic-acid-diethylamide-lsd-in-healthy-older-volunteers-potential-to-evaluate-as-disease-modifying-therapy-for-alzheimers-disease

  • share
  • Twitter
  • Facebook
  • LinkedIn


About Author

Mateen Dalal    

Mateen Dalal

Mateen has completed his Bachelor’s degree in electronics and telecommunication engineering, post which he lent his proficiency to the industry, working as a quality and test engineer. Drawn intricately toward the field of content creation however, Mateen soon switc...

Read More

More News By Mateen Dalal

UAE extends travel ban for Indians amid strict COVID-19 guidelines
UAE extends travel ban for Indians amid strict COVID-19 guidelines
By Mateen Dalal

United Arab Emirates (UAE) has reportedly extended travel ban for individuals travelling from India and several other south Asian countries on the pretext of COVID-19 guidelines. As reported by Etihad Airlines, the ban will be followed till 31st July...

Adevinta Ventures backs Lovys's Series A follow-on investment round
Adevinta Ventures backs Lovys's Series A follow-on investment round
By Mateen Dalal

Adevinta Ventures, an investment arm of Adevinta, has announced its investment in French insurance service provider ‘Lovys’, marking as its first investment in France in the Fintech and Insurtech sector. With this investment, Adevinta Ve...

Indian EV startup eBikeGo expands fleet to 2,100, hires 70 employees
Indian EV startup eBikeGo expands fleet to 2,100, hires 70 employees
By Mateen Dalal

The company is aiming for achieving a 2% share in the Indian electric two-wheeler market, with plans to deploy 200,000 e-scooters across 100 cities eBikeGo, an electric vehicle startup, has recently revealed that it has increased its fleet of electr...