Dance Biopharm unveils positive Phase 2 trial data for inhaled insulin
Category: #health  By Mateen Dalal  Date: 2019-06-10
  • share
  • Twitter
  • Facebook
  • LinkedIn

Dance Biopharm unveils positive Phase 2 trial data for inhaled insulin

The new data further supports the potential of Dance 501 inhaled insulin in Type 2 diabetes patients

Dance Biopharm Holdings, Inc has recently presented Phase 2 Samba 04 clinical study results for its preservative free inhaled human insulin, Dance 501, for the treatment of Type 2 diabetes. Dance Biopharm is a privately-owned clinical stage biopharma company fully focused on the development of a new soft mist inhalable biologic formulations for those people suffering from chronic diseases.

Seemingly, in the results Dance 501 showed a faster onset of action for as compared to similar doses of subcutaneously administered insulin lispro. These findings were to be presented at the 79th Scientific Sessions of the American Diabetes Association, being organized in San Francisco.

According to Anne Whitaker, the chief executive officer of Dance Biopharm, the company’s presentation at ADA underscores ongoing commitment of Dance to develop advanced and patient-focused inhaled therapies that result to better health outcomes for people suffering with chronic diseases like diabetes.

Whitaker said that the new data further supports the potential of Dance 501, inhaled preservative free human inhaled insulin, which is an alternate treatment to injectable insulin for diabetes. These data determine the outstanding performance of soft mist inhaler platform and encourages the company to swiftly progress the development of its innovative soft mist biologics portfolio as treatments for chronic and severe diseases, Whitaker mentioned.

Sources familiar with the matter informed that this Phase 2 clinical trial, Samba 04, was designed as an open label, crossover, randomized, and active-comparator-controlled study that recruited 24 subjects with type 2 diabetes presently receiving metformin or insulin therapy. Each patient got three doses of subcutaneous insulin lispro and three doses of inhaled Dance 501 under medical administration or supervision.

Apparently, doses administered were 12, 24 and 48 U for both lispro and Dance 501. Each patient received all 6 doses during 6 visits that occurred 3 to 17 days apart. Using the automated glucose clamp method, insulin action was measured over a 10-hour period following dosing.

 

Source Credit: https://www.dancebiopharm.com/investors-and-media/press-releases/detail/18/dance-biopharm-presents-encouraging-data-from-phase-2

  • share
  • Twitter
  • Facebook
  • LinkedIn


About Author

Mateen Dalal    

Mateen Dalal

Mateen has completed his Bachelor’s degree in electronics and telecommunication engineering, post which he lent his proficiency to the industry, working as a quality and test engineer. Drawn intricately toward the field of content creation however, Mateen soon switc...

Read More

More News By Mateen Dalal

AgraFlora announces acquisition of outstanding shares of Sanna
AgraFlora announces acquisition of outstanding shares of Sanna
By Mateen Dalal

  Under the agreement terms, the company is required to pursue the acquisition of 100% of Sanna’s outstanding shares. The acquisition is anticipated to amplify the production capacity of AgraFlora to two times the current production by...

NantKwest announces Phase 1 results of PD-L1.t-haNK cell therapy
NantKwest announces Phase 1 results of PD-L1.t-haNK cell therapy
By Mateen Dalal

NantKwest Inc., a U.S.-based clinical-stage immunotherapy company, has reportedly announced encouraging safety data generated from the first six patients in its QUILT-3.064 clinical trial. The study is conducted to access the preliminary efficac...

Twitter launches a central hub for privacy and data protection info
Twitter launches a central hub for privacy and data protection info
By Mateen Dalal

  New website will host information on Twitter’s new privacy products and announcements Twitter is also looking to change its current data protection and privacy terms Twitter has recently launched a new website called Twitter Privac...